New Agilent 1200 Series LC Systems & Modules.
Now you get a winning combination of speed, resolution and
sensitivity that ensures faster access to a better quality of data.
The proven modular design ensures the reliability and investment
protection that Agilent Technologies stands for. No doubt the Agilent
1200 Series LC will meet your application requirements now and in the
future. Building on new ZORBAX column technology and novel system
design your analysis time will be shortened up to 20x. Resolution can
improve as much as 60%. More intuitive user interfaces will let you
instantaneously control and monitor the instrument status. New choices
in data analysis offer you rapid and efficient data review tools. The
Agilent diagnostic software enables Intelligent Services providing
more uptime, independent of the data system in use.
Spectral information from 190 to 950 nm
The dual-lamp design and the temperature control of the Agilent
1200 Series diode-array detectors ensure outstanding sensitivity.
Photodiode arrays with 1024 elements, programmable slit width (1, 2,
4, 8, 16 nm) and the selection of nine different flow cells enable
optimization of resolution, linearity and sensitivity.
Modular and scalable platform lets you decide just how fast you
want to work
First, decide just how fast you want to work. Then choose a system
that meets your requirements. With modular and scalable solutions from
binary and quaternary LC systems through to the ultra-fast 1200 series
ripid resolution system, Agilent empowers you to achieve new levels of
productivity, processing more samples in less time, while maintaining
and even improving data quality.
Agilent 1200 Binary Pump SL
Configurable delay volume down to 120 µL together with a flow
range up to 5 mL/min provides universal applicability
- Electronic damping control for lowest baseline noise
- Perfect choice for fast and precise gradients using LC/MS, as
well as UV-only systems
- Fully exploits the speed and separation potential of Zorbax
ripid resolution columns
Fast cycle time for ultra-fast analysis
- High performance autosamplers enable fast injection cycles
without sacrificing lowest carryover
- Valve solutions for alternating column regeneration
- Minimized run-to-run instrument and software initialization time
High temperature enables higher speed
The two independently controllable low volume heat exchangers allow
ultra-fast, high temperature separation with unique post-column
cooling for the lowest possible UV detection limits.
Easy maintenance and intelligent system monitoring for increased
- Long-life pistons and seals, together with active seal wash,
reduce the frequency of preventive maintenance.
- Deuterium and xenon lamps with a lifetime of over 2000 hours.
- Patented orthogonal spray design substantially reduces ion
source contamination and the need for cleaning.
- Easily interchangeable ion sources.
- E-Pac design significantly reduces assembly and disassembly time
Agilent system intelligence
- Early Maintenance Feedback (EMF) tracks system usage (such as
lamp burn time, solvent usage) and alerts you for timely
replacement of parts.
- Column identification module records column parameters (such as
number of injections, particle size, maximum pressure) and
provides a unique column signature.
- Patented RFID tracking technology in the Agilent 1200 diode
array detector SL saves all relevant meta data from the flow cells
and UV lamp.
- Control Area Network (CAN) provides inter-modular, real-time
communication for reliable operation, regardless of PC failures or
- Software independent LC diagnostic tool assists users and the
support experts interpreting the instrument status
- Agilent system intelligence provides a new generation of
services with on-demand remote connectivity for a new level of
Successful system validation for GLP, GCP, cGMP and 21 CFR11
Validating analytical hardware, software and methods–plus
ensuring data security, integrity and traceability can be
time-consuming and costly.Our hardware and software offer more
built-in compliance features than any other systems on the market. You
can validate your systems, methods and data in the shortest possible
time and at the lowest cost.
To make regulatory compliance even easier, Agilent Technologies
support services offer fast, affordable compliance solutions.
Five steps guide you to fast, cost-effective and successful
Step 1: Design qualification (DQ)
Design qualification is the first and most important step of any
qualification process. When done right, this can save a lot of time
for later qualification phases. For instruments this means:1.
Documentation of user requirements and instrument functional and
operational specifications2. Qualifying the vendor for appropriate
software development and support processesAgilent Technologies helps
you with:· An extensive list of functional specifications for
computer systems. Select appropriate functions and specifications to
develop DQ’s for your own intended use.· Documented evidence that
software and computer systems have been validated during development
according to standardized procedures · Comprehensive hardware
specifications that can be found on Agilent's product web pages. It is
the users’responsibility to validate the software they use, but
without access to the underlying programming routines, software
validation is a difficult task. Agilent Technologies validates each
product before it leaves the factory and provides documented and
certified evidence of sucessful software validation through:·
Compliance with industry standards such as GAMP · More than 100
successful audits by international pharmaceutical companies ·
Declaration of system validation shipped with each product ·
Documented development and validation process available on CD through
Step 2: Installation qualification (IQ) and operational
qualification/performance verification (OQ/PV)
Agilent Technologies helps you qualify your analytical instruments
for correct installation and operation in your laboratory. We
provide:· Software that verifies correct installation and operation
of your hardware and computer software · IQ and OQ/PV services for
hardware, standalone computer systems and networks · Standardized
global protocols fro instruments from multiple vendors · Audit-ready
documentation of qualification results, collected in binders or in
electronic form. With Agilent Technologies’s computer-aided
verification package, your complete system can be qualified in less
than four hours. Users can select the most suitable tests from a
comprehensive list of parameters and calculation modes, and define
their order.Each test registers flagged, pass or fail. If a test is
flagged or fails, the software offers tips for resolving the problem.
Step 3: Analytical method validation
You must validate analytical methods after their development and
before routine use. If you change any parameter significantly, you
must revalidate the method.National and international standards and
interpretation guides, such as those issued by the United States
Pharmacopeia (USP) and the International Conference on Harmonization (ICH)
organizations, specify parameters for method validation.Agilent offers
software for automated method validation with ChemStation Plus·
Supports all GxP regulations and 21 CFR Part 11 · Supports US adn
European Pharmacopeias · Offered with validation services · Use of
standard Microsoft Word as report generator for highest flexibility ·
Full system automation through seamless integration into the Agilent
1200 Series LC.
Step 4: Performance qualification (PQ)
Performance qualification can keep laboratory productivity high !
Ongoing control of instruments through performance qualification
maintains your laboratory’s productivity by avoiding results that
are unexpectedly out of specification. You also avoid troublesome
Our systems contain built-in features to reduce the time needed to
perform PQ and document results
- Permanent electronic records of lamp burn time, volumes of
solvent pumped over each seal, or the number of injections
performed on each valve rotor make it possible to schedule timely
preventive maintenance before an instrument error occurs.
- Automated self-verification and recalibration routines, such as
wavelength verification with built-in holmium oxide filters,
document specified and actual data on paper or on disk for easy
- System suitability software calculates critical chromatographic
performance parameters from standard runs and quality control
samples.The software can shut off the system if predefined
criteria are not met.
- On-line monitoring of network connectivity and traffic ensure
highest uptime of your applications running on the network.
Step 5: Electronic records protectionThe final step—protecting
the integrity, security and traceability of electronic records—is
the most critical. Success in meeting regulations such as 21 CFR Part
11 and in particular specifications for electronic signatures and
records hinges on securing the authenticity of the data you
generate.Furthermore, you must protect your data against unauthorized
disclosure, unintentional error and intentional fraud.Agilent
Technologies helps you by multiple levels of security built into the
ChemStation Plus· User logon and passwords safeguard access to
chromatography data as well as network and server resources. · You
can customize and manage access levels appropriate for each user. ·
No sample results are ever overwritten. The database maintains the
full electronics audit trail. · Instrument identification is recorded
automatically for improved traceability.